As a PhD student, I conduct research on mitochondrial fatty acid oxidation (FAO) disorders, with a particular focus on long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) and mitochondrial trifunctional protein deficiency (MTPD). My research primarily focuses on the mechanisms underlying peripheral neuropathy in these disorders and investigates how impaired fatty acid oxidation, mitochondrial dysfunction, and the accumulation of disease-associated metabolites affect Schwann cells and the peripheral nerve microenvironment.
I am particularly interested in mitochondrial bioenergetics, cellular metabolism, metabolomics, and the mechanisms linking defective fatty acid oxidation to neurological complications. My current PhD project explores crosstalk within the peripheral nerve microenvironment in LCHADD/MTPD and its implications for disease mechanisms and potential therapeutic strategies.
In my work, I am responsible for planning and conducting laboratory experiments, performing cell culture and mitochondrial function studies, analyzing metabolomics and other experimental data, interpreting results, and preparing scientific presentations and manuscripts.
